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1.
Arch. med. res ; 24(1): 33-6, mar. 1993. tab
Article in English | LILACS | ID: lil-176999

ABSTRACT

To determine the effect of low protein and cornbased diets on the maturation of cerebellum, three groups of young rats were fed during a period of 6 weeks with different diets; 23 and 8 percent of protein (purina-Chow base) and a corn-based diest (8 percent protein). At the end of that period, the concentrations of free amino acids in the cerebellum was measured. Glutamic acid, glucine, glutamine and serine showed the highest values in all groups studied. Corn-based diet group showed the lowest free amino acid concentration compared to that of the control group, with a significant diminutions in the concentration of glutamic acid, lysine, tyrosine and histidine. Differences between essential and nonessential amino acids were not observed in all groups studied. Although corn-based diet did not induce specific changes as those reported in severe malnutrition, its effects on the concentration of some amino acids other than tryptophan could have some physiological correlations which need to be further studied


Subject(s)
Animals , Rats , Animal Feed/adverse effects , Amino Acids/deficiency , Cerebellum/physiopathology , Protein Deficiency/chemically induced , Zea mays/toxicity , Rats/physiology
2.
Arch. invest. méd ; 19(2): 133-8, abr.-jun. 1988. tab, ilus
Article in English | LILACS | ID: lil-74366

ABSTRACT

El proposito de este trabajo fue observar si existen diferencias significativas en el comportamiento de desnaturalización de las proteinas presentes en la secreción viginal humana a traves del método polarográfico de Brdicka. Nuestros resultados muestran que tanto la prueba del digerido como la del filtrado son significativamente diferentes en al secreción vaginal de mujeres en las cuales se ha diagnosticado la presencia de cancer cervicouterino por los procedimientos usuales (citología, colposcopia e biopsia). Estas diferencias son particularmente claras cuando los resultados de la prueba del digerido y los de la prueba del filtrado se relacionan a traves del índice proteico, en el cual casi no hay sobreposición entre los casos normales y los patológicos (15.8 + 4.8 contra 4.2 + 2.0 respectivamente) aun cuando se toma en cuenta el promedio + dos desviaciones estandar. Proponemos que esta prueba podria ser una adición de valorar a los procedimientos de diagnostico y pronostico del carcinoma de cervix in situ, particularmente en los paises subesarrollados


Subject(s)
Humans , Female , Carcinoma in Situ/diagnosis , Uterine Cervical Neoplasms/diagnosis , Vagina/metabolism
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